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Most Extreme Humans

Follow incredible people from around the globe who are living with the world’s rarest medical conditions...

Series
Reality
Medical
Released 2026
Broadcaster TLC
Key Personnel
S Am Profile

Sam Ornbo

Showrunner

S Am Profile
1000043680

Amy Gostling

Line Producer

1000043680
Most Extreme Humans Key Art Landscape 1

Explore the unfiltered lives of people with extraordinary physical conditions, rare medical challenges, and remarkable transformations as they navigate everyday life, relationships, and the pursuit of their dreams.

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